Crimean-Congo haemorrhagic fever outbreak in Middle Anatolia: a multicentre study of clinical features and outcome measures.
نویسندگان
چکیده
A Crimean-Congo haemorrhagic fever (CCHF) outbreak emerged from 2001 to 2003 in the Middle Anatolia region of Turkey. This study describes the clinical characteristics and outcome features of CCHF patients admitted to four tertiary care hospitals in Turkey. Definitive diagnosis was based on the detection of CCHF virus-specific IgM by ELISA or of genomic segments of the CCHF virus by RT-PCR. Related data were collected by a retrospective chart review. Hospital costs were extracted from the final discharge bills. Univariate and multivariate analyses were conducted to determine the independent predictors of mortality. CCHF virus-specific antibodies or genomic segments were detected in the sera of 99 cases. Seven cases that were treated with ribavirin were excluded from the study. Cases were mostly farmers (83 cases, 90 %), and 60 % had a tick-bite history before the onset of fever. Impaired consciousness and splenomegaly were independent predictors of a fatal outcome.
منابع مشابه
Reply: Surveillance of Crimean-Congo Haemorrhagic Fever in Pakistan
[No Abstract] To the editor: In a recent publication entitle “Surveillance of Crimean-Congo haemorrhagic fever in Pakistan” published in “The Lancet Infectious Diseases”, the authors claimed that before the Eid al-Adha, Crimean-Congo Hemorrhagic Fever (CCHF)-livestock infected are imported from Iran and Afghanistan to Baluchistan province of Pakistan and then tran...
متن کاملTHE EFFICACY OF ORAL RIBAVIRIN IN THE TREATMENT OF 81 PROVED CASES OF CRIMEAN-CONGO HEMORRHAGIC FEVER (CCHF) IN IRAN (1999-2001)
Crimean-Congo Hemorrhagic Fever is a fatal viral disease that occurs in some parts of Africa, Asia, Eastern Europe and the Middle-East. Primarily it is a zoonosis but can be seen sporadically in humans. Recently outbreaks have been reported from Pakistan, Afghanistan, Saudi Arabia, United Arab Emirates and Iran. In this retrospective study, we evaluated the efficacy of oral Ribavirin in the...
متن کاملSerologic Survey of Crimean-Congo Haemorrhagic Fever among Sheep in Ardabil Province, Northwest Iran
Introduction: Livestock is a known source of Crimean-Congo Hemorrhagic Fever (CCHF) virus infection in humans. Although CCHF is endemic in Iran, limited human cases of CCHF are reported from northwest of Iran. Considering the lack of complete and updated information on the status and distribution of CCHF infection among domestic animals in Ardabil province, this study was conducted to investiga...
متن کاملShewanella haliotis Associated with Severe Soft Tissue Infection, Thailand, 2012
1. Grard G, Drexler JF, Fair J, Muyembe JJ, Wolfe ND, Drosten C, et al. Re-emergence of Crimean-Congo hemorrhagic fever virus in Central Africa. PLoS Negl Trop Dis. 2011;5:e1350. http://dx.doi. org/10.1371/journal.pntd.0001350 2. Mild M, Simon M, Albert J, Mirazimi A. Towards an understanding of the migration of Crimean-Congo hemorrhagic fever virus. J Gen Virol. 2010;91:199–207. http://dx.doi....
متن کاملHealthcare-associated Crimean-Congo haemorrhagic fever in Turkey, 2002–2014: a multicentre retrospective cross-sectional study
Healthcare-related transmission of Crimean-Congo haemorrhagic fever (CCHF) is a well-recognized hazard. We report a multicentre retrospective cross-sectional study undertaken in Turkey in 2014 in nine hospitals, regional reference centres for CCHF, covering the years 2002 to 2014 inclusive. Data were systematically extracted from charts of all personnel with a reported health care injury/accide...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Journal of medical microbiology
دوره 54 Pt 4 شماره
صفحات -
تاریخ انتشار 2005